Company: University of Eastern Finland & University of Tübingen
Job title: Professor of Drug Design
Antti Poso is a Professor of Drug Design at School of Pharmacy, University of Eastern Finland and Distinguished Guest Professor at University of Tübingen, Germany. His main interest areas are molecular modelling, anti-cancer and anti-bacterial drug design.
Allosteric Modulation of KRAS by G12X Mutations 9:30 am
KRAS long timescale dynamics investigated by extensive atomistic molecular dynamics simulations reveals complex allosteric signaling network within the protein Dynamics of KRAS is altered by G12X missense mutants via the hydrophobic allosteric network. This is mutation-specific and the effect on KRAS dynamics is especially manifested in the effector protein binding interface Different KRAS G12X mutations…Read more
day: Day One