Aparajita Hoskote Chourasia
Job title: Senior Scientist & Team Leader
Aparajita Chourasia is a Senior Scientist & Team Leader at BioTheryX spearheading early drug discovery projects in oncology and inflammation. Her research focuses on identification and validation of novel substrates of BioTheryX’s Cereblon binding small molecules and PROTACs, as well as understanding their downstream biology. She has over 10 years of experience in molecular pathways in cancer, tumor models and assay development. She has a demonstrated record of collaborative work with highly diverse teams comprising of industry scientists, academicians and clinicians. She received her doctoral degree from the University of Chicago.
Targeted Protein Degradation as a Therapeutic Strategy for RAS-Driven Cancers 3:30 pm
Targeted protein degradation is the next generation drug discovery platform for successfully attacking previously “undruggable” targets such as RAS Developing small molecule cereblon-directed Protein Homeostatic Modulators (PHMs™) – molecular glue – to selectively target oncogenic RAS activation Develop PROTACs that target RAS to explore their potential in oncologyRead more
day: Day Two