Company: Farber Cancer Institute
Job title: Research Fellow- Dana
Behnam Nabet, Ph.D. is a Postdoctoral Research Fellow in the laboratory of Dr. Nathanael Gray at the Dana-Farber Cancer Institute. Dr. Nabet received his Ph.D. in Cancer Biology from Northwestern University and B.A. in Biology from the University of Pennsylvania. In his postdoctoral research, Dr. Nabet developed a generalizable technology platform known as the dTAG system to rapidly degrade any target protein of interest. The dTAG system pairs potent small molecule degraders and extensible tagging strategies to achieve selective degradation of divergent proteins. This technology facilitates biological exploration and drug target validation in cells and animal models. Dr. Nabet is currently applying the dTAG platform to investigate pancreatic cancer dependencies and has been sharing the technology with the global scientific community in an open-source manner. Dr. Nabet is supported by an American Cancer Society Postdoctoral Fellowship and is a recipient of the Claudia Adams Barr Program for Innovative Cancer Research award.
Leveraging Targeted Protein Degradation to Tackle Cancer Dependencies 4:00 pm
Advances in targeted protein degradation Challenges and promise of targeting KRAS for degradation Case studies highlighting functional evaluation of cancer dependencies including KRAS using the dTAG systemRead more
day: Day Two