Frantz Jean- Francois
Company: RAS initiative Frederick National Laboratory for Cancer Research
Job title: Team Lead
Seminars:
Live Panel Q&A – Ask the Speakers Your Burning Questions 12:50 pm
day: Day Two
PROTAC Mediated Degradation of KRAS 12:00 pm
KRAS PROTACs that employ novel ubiquitin ligase and degrade different KRAS isoforms will be the subject of this talk Current methods for PROTAC discovery are not optimal. Use of PROTAC mediated in-vitro ubiquitination to expedite discovery of novel PROTACs Me too ligase, VHL and Cereblon do not offer specificity for certain targets. Relationship between in…Read more
day: Day Two