Hanna Budayeva

Hanna Budayeva

Company: Genentech

Job title: Principal Scientific Researcher


Increasing the Throughput of Ligandable Cysteine Hotspots Profiling by Mass Spectrometry to Guide RAS Pathway Drug Discovery 3:15 pm

Hotspots are accessible, reactive and ligandable residues that can serve as covalent drug targets Systematic cataloging of the hotspots present in a cellular proteome is instrumental for advancements in drug discovery We implemented sample hyperplexing into an activity-based proteome profiling (ABPP) workflow to increase the depth and throughput of ligandable cysteine hotspots identification by mass…Read more

day: Day One

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