Jim Vasta

Jim Vasta

Company: Promega

Job title: Senior Research Scientist

Seminars:

Live Panel Q&A – Ask the Speakers Your Burning Questions 10:40 am

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day: Day One

Reversible Switch-2 Pocket Engagement Across KRAS Hotspot Mutants in Cells 10:15 am

We have developed a novel live-cell target engagement assay for the formerly undruggable RAS using the NanoBRET target engagement approach The assay is capable of observing inhibitors of multiple mechanisms and can be utilized in a screening environment to detect weak affinity fragments with micromolar affinity We have found that KRAS and various KRAS hotspot…Read more

day: Day One

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