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Mariano Barbacid

Mariano Barbacid

Company: Spanish National Cancer Research Center (CNIO)

Job title: AXA-CNIO Professor of Molecular Oncology and Head of the Experimental Oncology Group


Targeting KRAS Mutant Lung and Pancreatic Tumors 1:00 pm

Genetic studies using genetically engineered KRAS/TP53-driven mouse lung and pancreatic tumor models (including a KRASG12C strain) with which we have validated the therapeutic potential of K-RAS itself as a target as well as of each of the downstream kinases of the MAPK and PI3K pathways Our results illustrate the toxic consequences of genetically ablating or…Read more

day: Day Two

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