Poulikos Poulikakos
Company: Icahn School of Medicine at Mount Sinai
Job title: Associate Professor
Seminars:
Live Panel Q&A – Ask the Speakers Your Burning Questions 3:15 pm
day: Day Two
Live Panel Q&A – Ask the Speakers Your Burning Questions 1:30 pm
day: Day One
Targeting Adaptive Resistance to RAS/MAPK-Directed Therapies 12:25 pm
Adaptive resistance and RAS/MAPK reactivation limits therapeutic response to RAS/MAPK targeting agents Development of inhibitors targeting components of the RAS/MAPK adaptive machinery (inhibitors of RTKs, SHP2, SOS, dimeric RAF) enables the development of more effective combinatorial therapeutic approaches Effective targeting of components of RAS/MAPK in their native conformations in cells requires elucidating and exploiting allosteric…Read more
day: Day One