Company: New York University School of Medicine and Perlmutter Cancer Center
Job title: Professor of Biologics Design
Shohei Koide, Ph.D. is a synthetic protein scientist. His research integrates structure-guided design and directed evolution to design highly functional but still simple proteins. He is the inventor of the FN3 Monobody technology, and he has made important contribution to the development of synthetic antibody technologies. His current research focuses on the discovery of cancer therapeutics and on establishing strategies to control “undruggable” targets. Previously he was Professor at University of Chicago and at University of Rochester School of Medicine and Dentistry.
Discovery of Novel RAS Vulnerability using Monobodies 4:45 pm
The current challenge in developing RAS-targeting drugs suggests the need for innovative approaches for discovering methods to control RAS function We have established a platform to rapidly develop monobodies, synthetic binding proteins, with high selectivity and potency and to utilize them as genetically encoded “tool” biologics against intracellular targets such as RAS Our approach has…Read more
day: Day One